Tuscany Diet - Biochemistry And Metabolism : Différence entre versions

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Version actuelle datée du 29 décembre 2025 à 08:18


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The CK does channel ATP from sites of manufacturing to buffer free ADP and Pi (free phosphate) concentrations. CK (creatine kinase) is localized on the mitochondrial membrane, on the M- and that i-band, and on the SR membrane (Rossi et al. 1990; Wegmann et al. 1992; Wallimann et al. 2011). CK may be current within the triad, but to our information this has not been demonstrated. From a functional side, there is a transparent association of muscle glycogen contents and muscle function in experiments with the mechanically skinned fibre (Stephenson et al. 1999; Nielsen et al. 2009). This association has been established under circumstances where ATP and PCr are saved high and constant. Furthermore, the t-tubular Na,K-ATPase operate is improved by addition of phospho(enol)pyruvate (supported by endogenous pyruvate kinase bound within the triad) even with forty mm PCr current (Dutka & Lamb, 2007). Together, these results show that the triad junction is a extremely restricted microenvironment, which may not be adequately buffered by CK channelling.

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