Detecting Myocardial Ischemia At Rest With Cardiac Phase-Resolved Blood Oxygen Level-Dependent Cardiovascular Magnetic Resonance : Différence entre versions
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| − | <br>Tsaftaris, Sotirios A. and Zhou, | + | <br>Tsaftaris, Sotirios A. and Zhou, Xiangzhi and Tang, Richard and Li, Debiao and Dharmakumar, Rohan Detecting Myocardial Ischemia at Rest With Cardiac Phase-Resolved Blood Oxygen Level-Dependent Cardiovascular Magnetic Resonance. Circulation: Cardiovascular Imaging, 6 (2). pp. Background: Fast, noninvasive identification of ischemic territories at relaxation (prior to tissue-particular changes) and evaluation of functional standing may be helpful in the management of severe coronary artery disease. This research investigated the utility of cardiac section-resolved Blood-Oxygen-Level-Dependent (CP-Bold) CMR in detecting myocardial ischemia at rest secondary to severe coronary artery stenosis. 11) at baseline and inside 20 minutes of ischemia induction (extreme LAD stenosis) at relaxation. Following 3-hours of ischemia, LAD stenosis was removed and T2-weighted and late-gadolinium-enhancement (LGE) photographs have been acquired. From commonplace-cine and CP-Bold images, End-Systolic (ES) and End-Diastolic (ED) myocardium were segmented. Affected and remote sections of the myocardium had been identified from put up-reperfusion LGE photographs. S/D, quotient of mean ES and ED sign intensities (on CP-Bold and commonplace-cine), was computed for affected and distant segments at baseline and ischemia. Ejection fraction (EF) and segmental wall-thickening (sWT) have been derived from CP-Bold images at baseline and ischemia.<br><br><br><br>Disclosure: The authors haven't any conflicts of interest to declare. Correspondence: Thomas MacDonald, Medicines Monitoring Unit and Hypertension Research Centre, Division of Medical Sciences, University of Dundee, Ninewells Hospital & Medical School, Dundee DD1 9SY, UK. Hypertension is the commonest preventable cause of cardiovascular illness. Home blood pressure monitoring (HBPM) is a self-monitoring software that can be included into the care for patients with hypertension and is really helpful by main pointers. A rising body of proof helps the benefits of patient HBPM in contrast with office-primarily based monitoring: these embody improved management of BP, diagnosis of white-coat hypertension and prediction of cardiovascular danger. Furthermore, HBPM is cheaper and [https://patrimoine.minesparis.psl.eu/Wiki/index.php/Utilisateur:UWFVirgie2885 home SPO2 device] easier to perform than 24-hour ambulatory BP monitoring (ABPM). All HBPM devices require validation, nevertheless, as inaccurate readings have been present in a high proportion of screens. New know-how options an extended inflatable space inside the cuff that wraps all the best way round the arm, rising the ‘acceptable range’ of placement and thus decreasing the impression of cuff placement on reading accuracy, thereby overcoming the constraints of current units.<br><br><br><br>However, even though the influence of BP on CV threat is supported by one in all the best our bodies of clinical trial knowledge in medication, few clinical studies have been dedicated to the problem of BP measurement and its validity. Studies additionally lack consistency in the reporting of BP measurements and a few don't even present details on how BP monitoring was carried out. This article aims to debate the benefits and disadvantages of home BP monitoring (HBPM) and examines new know-how aimed at enhancing its accuracy. Office BP measurement is related to several disadvantages. A research through which repeated BP measurements were made over a 2-week interval below analysis examine circumstances found variations of as much as 30 mmHg with no treatment modifications. A latest observational research required main care physicians (PCPs) to measure BP on 10 volunteers. Two trained research assistants repeated the measures immediately after the PCPs.<br><br><br><br>The PCPs had been then randomised to obtain detailed training documentation on standardised BP measurement (group 1) or details about excessive BP (group 2). The BP measurements have been repeated just a few weeks later and the PCPs’ measurements in contrast with the common value of 4 measurements by the analysis assistants (gold standard). At baseline, the mean BP variations between PCPs and the gold standard had been 23.0 mmHg for systolic and 15.Three mmHg for diastolic BP. Following PCP coaching, the imply difference remained high (group 1: 22.Three mmHg and 14.Four mmHg; group 2: 25.3 mmHg and 17.0 mmHg). Because of the inaccuracy of the BP measurement, 24-32 % of volunteers had been misdiagnosed as having systolic hypertension and 15-21 % as having diastolic hypertension. Two alternative applied sciences can be found for measuring out-of-workplace BP. Ambulatory BP monitoring (ABPM) gadgets are worn by patients over a 24-hour interval with a number of measurements and are considered the gold commonplace for BP measurement. It also has the advantage of measuring nocturnal BP and therefore permitting the detection of an attenuated dip throughout the night time.<br><br><br><br>However, ABPM monitors are costly and, while cost-efficient for the analysis of hypertension, should not sensible for the long-term monitoring of BP. Methods for non-invasive BP measurement embrace auscultatory, oscillometric, tonometry and pulse wave document and evaluation. HBPM uses the identical know-how as ABPM screens, however allows patients to watch BP as typically as they want. The advantages and disadvantages of HBPM are summarised in Table 1. While ABPM gives BP information at many timepoints on a specific day throughout unrestricted routine every day activities, HBPM offers BP information obtained below mounted instances and conditions over a protracted interval; thus, HBPM offers stable readings with high reproducibility and has been shown to be as dependable as ABPM. Table 1: Advantages and Limitations of [https://cse.google.md/url?sa=t&url=http://kuma.wisilicon.com:4000/tammara98m6691 home SPO2 device] Blood Pressure Monitoring. BP recording continues for not less than four days, ideally for 7 days. Measurements taken on the first day must be discarded and the average value of the remaining days after day one is discarded be used.<br> |
Version actuelle datée du 5 décembre 2025 à 03:22
Tsaftaris, Sotirios A. and Zhou, Xiangzhi and Tang, Richard and Li, Debiao and Dharmakumar, Rohan Detecting Myocardial Ischemia at Rest With Cardiac Phase-Resolved Blood Oxygen Level-Dependent Cardiovascular Magnetic Resonance. Circulation: Cardiovascular Imaging, 6 (2). pp. Background: Fast, noninvasive identification of ischemic territories at relaxation (prior to tissue-particular changes) and evaluation of functional standing may be helpful in the management of severe coronary artery disease. This research investigated the utility of cardiac section-resolved Blood-Oxygen-Level-Dependent (CP-Bold) CMR in detecting myocardial ischemia at rest secondary to severe coronary artery stenosis. 11) at baseline and inside 20 minutes of ischemia induction (extreme LAD stenosis) at relaxation. Following 3-hours of ischemia, LAD stenosis was removed and T2-weighted and late-gadolinium-enhancement (LGE) photographs have been acquired. From commonplace-cine and CP-Bold images, End-Systolic (ES) and End-Diastolic (ED) myocardium were segmented. Affected and remote sections of the myocardium had been identified from put up-reperfusion LGE photographs. S/D, quotient of mean ES and ED sign intensities (on CP-Bold and commonplace-cine), was computed for affected and distant segments at baseline and ischemia. Ejection fraction (EF) and segmental wall-thickening (sWT) have been derived from CP-Bold images at baseline and ischemia.
Disclosure: The authors haven't any conflicts of interest to declare. Correspondence: Thomas MacDonald, Medicines Monitoring Unit and Hypertension Research Centre, Division of Medical Sciences, University of Dundee, Ninewells Hospital & Medical School, Dundee DD1 9SY, UK. Hypertension is the commonest preventable cause of cardiovascular illness. Home blood pressure monitoring (HBPM) is a self-monitoring software that can be included into the care for patients with hypertension and is really helpful by main pointers. A rising body of proof helps the benefits of patient HBPM in contrast with office-primarily based monitoring: these embody improved management of BP, diagnosis of white-coat hypertension and prediction of cardiovascular danger. Furthermore, HBPM is cheaper and home SPO2 device easier to perform than 24-hour ambulatory BP monitoring (ABPM). All HBPM devices require validation, nevertheless, as inaccurate readings have been present in a high proportion of screens. New know-how options an extended inflatable space inside the cuff that wraps all the best way round the arm, rising the ‘acceptable range’ of placement and thus decreasing the impression of cuff placement on reading accuracy, thereby overcoming the constraints of current units.
However, even though the influence of BP on CV threat is supported by one in all the best our bodies of clinical trial knowledge in medication, few clinical studies have been dedicated to the problem of BP measurement and its validity. Studies additionally lack consistency in the reporting of BP measurements and a few don't even present details on how BP monitoring was carried out. This article aims to debate the benefits and disadvantages of home BP monitoring (HBPM) and examines new know-how aimed at enhancing its accuracy. Office BP measurement is related to several disadvantages. A research through which repeated BP measurements were made over a 2-week interval below analysis examine circumstances found variations of as much as 30 mmHg with no treatment modifications. A latest observational research required main care physicians (PCPs) to measure BP on 10 volunteers. Two trained research assistants repeated the measures immediately after the PCPs.
The PCPs had been then randomised to obtain detailed training documentation on standardised BP measurement (group 1) or details about excessive BP (group 2). The BP measurements have been repeated just a few weeks later and the PCPs’ measurements in contrast with the common value of 4 measurements by the analysis assistants (gold standard). At baseline, the mean BP variations between PCPs and the gold standard had been 23.0 mmHg for systolic and 15.Three mmHg for diastolic BP. Following PCP coaching, the imply difference remained high (group 1: 22.Three mmHg and 14.Four mmHg; group 2: 25.3 mmHg and 17.0 mmHg). Because of the inaccuracy of the BP measurement, 24-32 % of volunteers had been misdiagnosed as having systolic hypertension and 15-21 % as having diastolic hypertension. Two alternative applied sciences can be found for measuring out-of-workplace BP. Ambulatory BP monitoring (ABPM) gadgets are worn by patients over a 24-hour interval with a number of measurements and are considered the gold commonplace for BP measurement. It also has the advantage of measuring nocturnal BP and therefore permitting the detection of an attenuated dip throughout the night time.
However, ABPM monitors are costly and, while cost-efficient for the analysis of hypertension, should not sensible for the long-term monitoring of BP. Methods for non-invasive BP measurement embrace auscultatory, oscillometric, tonometry and pulse wave document and evaluation. HBPM uses the identical know-how as ABPM screens, however allows patients to watch BP as typically as they want. The advantages and disadvantages of HBPM are summarised in Table 1. While ABPM gives BP information at many timepoints on a specific day throughout unrestricted routine every day activities, HBPM offers BP information obtained below mounted instances and conditions over a protracted interval; thus, HBPM offers stable readings with high reproducibility and has been shown to be as dependable as ABPM. Table 1: Advantages and Limitations of home SPO2 device Blood Pressure Monitoring. BP recording continues for not less than four days, ideally for 7 days. Measurements taken on the first day must be discarded and the average value of the remaining days after day one is discarded be used.