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- 2 - ABSTRACT With 26 letters we can form ail the words we use, and with a few words it is possible to form an infinité number of différent meaningful sentences. In our case,the letters will be a few simple neighborhood image transformations and area measûrements. The paper shows how, by iterating these trans¬ formations, it is possible to obtain a good quantitative des¬ cription of the nuclear structure of Feulgen-stained lymphocytes (CLL and normal). The fact that we restrict ourself to a small number of image transformations made it possible to construct an image analysis System able to do these transformations very quickly (TAS). We will see,, successively, how to segment the nucleus itself, the chromatin and the interchromatinic channels, how openings and closings lead to size and spatial distribution curves,and how skeletons may be used for measuring the lengths of interchromatinic channels. Key words : Mathematical Morphology, segmentation, size distri¬ bution, skeletons, quantitative cytology, nuclear texture.